DOSING & ADMINISTRATION

With its once-daily oral dosing, SOTYKTU
offers patients a convenient option1*

The recommended dose of SOTYKTU is 6 mg orally once daily, with or without food

Dose adjustments not required

For patients ≥65 years, with renal impairment, or with mild or moderate hepatic impairment.

Dose titration not required

Drug-drug interactions minimal

(per the clinical trials)

SOTYKTU is not recommended in combination with other potent immunosuppressants.

    Other considerations:
  • Not to be initiated in patients with any clinically important active infection until it resolves or is adequately treated
  • Evaluate for TB infection prior to initiating SOTYKTU. Do not administer SOTYKTU to patients with active TB
  • Prior to initiating SOTYKTU, consider
    completion of all age-appropriate
    immunizations according to current
    immunization guidelines
  • Not recommended in patients with severe hepatic impairment (Child-Pugh Class C)

Please see the Product Monograph for complete dosing, administration, and drug interactions information.

TB= tuberculosis
* Clinical significance unknown.
Major drug interactions that result in meaningful changes in exposure of deucravacitinib via inhibition or induction of a pathway are not
anticipated.
References:
1. SOTYKTU Product Monograph. Bristol-Myers Squibb Canada Co. November 23, 2022.

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